Prepared by the AABB Pathogen Inactivation Technology Review Work Group
The Food and Drug Administration (FDA) has approved pathogen inactivation (PI) technologies that can be employed as an additional safety measure to help maintain a safe blood supply. The FDA has approved the INTERCEPT Blood System (Cerus Corp, Concord, CA) for pathogen reduction of 1) apheresis platelets stored in plasma and platelet additive solution (PAS) and 2) plasma. The FDA has also approved an additional pathogen-reduced plasma product, Octaplas (Octapharma, Vienna, Austria) that uses a solvent/detergent method. This document focuses solely on pathogen-reduced platelets treated using the INTERCEPT Blood System method.
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NEW JERSEY ASSOCIATION OF BLOOD BANK PROFESSIONALS